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In this regard, mGluR plasticity has been described at the thalamocortical synapse in the somatosensory cortex, perhaps indicating that this form of plasticity is also present at the mediodorsal thalamic synapses in the PFC. This review examines the possibility 1 that LTD mechanisms are enhanced in the prefrontal cortex during adolescence due to ongoing synaptic pruning in this late developing cortex and 2 that enhanced synaptic plasticity in the prefrontal cortex represents a key molecular substrate underlying the critical period for maturation of executive function. Ann NY Acad Sci.
However, at the thalamocortical synapse, mGluR LTD acts presynaptically to decrease transmitter release and depress synaptic activity. Although reduction of synaptic connectivity might be accompanied by retraction of glial and neuronal processes, elimination of neuronal cell bodies occurs much earlier in development.
Abstract Flush heart maturation is characterized by the boredom of attractive forward mediated by the best cortex, e. J Clin Exp Neuropsychol.
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